Trp53

TRP53 activates a global autophagy program to promote tumor suppression ...

Trp53 controls chondrogenesis and endochondral ossification by negative ...

A) Immunohistochemical staining of TRP53 in the placental labyrinth ...

Mammary-specific expression of mutant Trp53 in an Amphiregulin knockout ...

Cre-mediated recombination of floxed Trp53 alleles affects the majority ...

(a) Schematic representation of Trp53 gene-targeting strategy. Red ...

Mutant TRP53 proteins exert a target geneselective DNE. (A ...

Mutant p53 promotes ESCC invasion and lung metastasis. (A, left) Trp53 ...

TRP53 Mutants Drive Neuroendocrine Lung Cancer Through Loss-of-Function ...

A summary of the ligand-mediated control of TRP53 expression via the ...

(a) Schematic representation of Trp53 gene-targeting strategy. Red ...

Expression of Trp53 mRNA within preimplantation stage embryos. RTPCR ...

Mutant TRP53 exerts a target gene-selective dominant-negative effect to ...

Generation of Trp53 −/− ;Nf1 −/− and Trp53 −/− ;Pten −/− ID8 cells. (A ...

Trp53 inactivation potentiates mitotic defects induced by ATRIP loss ...

Targeting the TRP53 binding site in the Nprl3 promoter accelerates ...

Trp53 Deletion Promotes Exacerbated Colitis, Facilitates Lgr5+ Cancer ...

(A) Relative mRNA expression levels of Trp53 and Pten at 48, 72, and 96 ...

Mutant TRP53 proteins exert a target geneselective DNE. (A ...

Trp53 controls chondrogenesis and endochondral ossification by negative ...

Generation of triple-deleted Trp53 −/− ;Brca2 −/− ;Pten −/− ID8 cells ...

Trp53 Mutation in Keratin 5 (Krt5)-Expressing Basal Cells Facilitates ...

Increased genomic instability in Rb1 DL/DL ; Trp53 À/À thymic lymphoma ...

Trp53 Deletion Promotes Exacerbated Colitis, Facilitates Lgr5+ Cancer ...

The hot spot mutant TRP53 proteins R246Q and R270H selectively ...

Trp53 72P activates Trp53-dependent DNA-repair target gene promoters ...

Genetic Inactivation of Notch1 Synergizes with Loss of Trp53 to Induce ...

The Trp53 R270 mutant allele mediates alterations in expression levels ...

Somatic Trp53 mutations differentially drive breast cancer and ...

Trp53 Deletion Promotes Exacerbated Colitis, Facilitates Lgr5+ Cancer ...

Trp53 R172H , not wild-type p53, binds to YAP and fosters Survivin ...

Genes & Cancer | Loss of TRP53 (p53) accelerates tumorigenesis and ...

Loss of one Trp53 allele leads to an increased pro-inflammatory ...

Mutant TRP53 exerts a target gene-selective dominant-negative effect to ...

Introduction of Trp53 mutations in Nbs1-deficient brain largely rescues ...

Genetic Inactivation of Notch1 Synergizes with Loss of Trp53 to Induce ...

Preneoplastic Trp53+/– mammary organoids mimic features of Trp53 ...

CRISPR/Cas9-mediated Trp53 and Brca2 knockout to generate improved ...

Combined Vhl, Trp53 and Rb1 mutation causes clear cell renal cell ...

Trp53 Deletion Promotes Exacerbated Colitis, Facilitates Lgr5+ Cancer ...

Notch1 and Trp53 deletion in Hes5 + cells leads to formation of ...

Trp53 knockout leads to ATC transformation and loss of... | Download ...

Mutant p53 promotes ESCC invasion and lung metastasis. (A, left) Trp53 ...

Trp53 and Pten had weak cooperative function in suppressing pituitary ...

Trp53 inactivation rescues apoptosis, morphological defects and visual ...

Trp53 F/F ;K14Cre;myrAkt tumors bypass senescence and phenocopy human ...

Combined Notch1/Notch2 and Trp53 deletion in Hes5 + cells leads to ...

CRISPR–Cas9-mediated gene disruption of Trp53 in WEA and WEP cancer ...

Trp53 Mutation in Keratin 5 (Krt5)-Expressing Basal Cells Facilitates ...

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by ...

The effect of Trp53 gene dosage on embryo development in vitro ...

Mutant Trp53 accelerates BRAF(V600E)-driven melanomagenesis. a, Trp53 ...

A transactivation-deficient mouse model provides insights into Trp53 ...

Generation and characterization of isogenic cell lines expressing Trp53 ...

Mammary tumor formation in the Trp53 knockout (KO) iKrasG12D mouse ...

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by ...

Atmin regulates Pdgfra expression in a mutant Trp53 background. (A ...

Depletion of Trp53 and Cdkn2a Does Not Promote Self-Renewal in the ...

Combined scheme showing irradiation-induced Trp53 molecular signalling ...

Deletion of Trp53 and Rb1 increases the expansion and differentiation ...

Endothelial-specific Trp53 deletion inhibits KP tumor regrowth after ...

Trp53 | KO Atlas

Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog ...

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by ...

Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog ...

KMT5c modulates adipocyte thermogenesis by regulating Trp53 expression ...

Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity ...

(a) Trp53 expression in undifferentiated ES cells. OCRG9 ES cells ...

TRP53 Mutants Drive Neuroendocrine Lung Cancer Through Loss-of-Function ...

Detection of Trp53 and phospho-Trp53 in non-irradiated cells and cells ...

(PDF) Genomic and functional impact of Trp53 inactivation in JAK2V617F ...

Genomic and functional impact of Trp53 inactivation in JAK2V617F ...

Phenotypic changes induced by Trp53 KD. (A) Real-time PCR analysis of ...

TRP53 amplification in mouse embryo stage E11.5. Amplification ...

Mammary tumor formation in the Trp53 knockout (KO) iKrasG12D mouse ...

Trp53 Haploinsufficiency Modifies EGFR-Driven Peripheral Nerve Sheath ...

Nucks1 synergizes with Trp53 to promote radiation lymphomagenesis in ...

High rates of aneuploidy in Trp53 and Vhl/Trp53 null MEFs.A.Western ...

TP53,BCC7,LFS1,P53,TRP53 癌基因 - 基因医生

The Trp53-Trp53inp1-Tnfrsf10b Pathway Regulates the Radiation Response ...

A model for the Trp53-mediated downregulation of Notch signaling. The ...

A schematic illustration of the for TP53/Trp53 mutation and metastasis ...

Pten;Kras;(Trp53) and Pten;Kras;(Trp53) mutant OSE cells are ...

生物医药靶点赛道：p53 p53 的生理作用 由“抑癌基因” TP53 转录出的 p53 蛋白是人类生理健康的“守护者”，其任务是根据致癌基因 ...

Direct in vivo editing of Prkar1a/Trp53 or Axin1/Trp53 genes in the ...

Trp53(−/−) FAP transplantation impairs muscle regeneration after acute ...

Induction of small cell lung cancer by somatic inactivation of both ...

Trp53-dependent endogenous DNA-repair target genes are activated more ...

Deletions linked to TP53 loss drive cancer through p53–independent ...

The genomic organization of the human and mouse p53 gene. (A) Both the ...

p53 status in TR and TRP L tumors and cortex. (A) Representative images ...

A schematic illustration of the for TP53/Trp53 mutation and metastasis ...

Protein interactions between Trp53, Mdm2 and NICD.... | Download ...

Regulation of male germline transmission patterns by the Trp53-Cdkn1a ...

Induction of small cell lung cancer by somatic inactivation of both ...

Oncogenic and teratogenic effects of Trp53Y217C, an inflammation-prone ...

Figure 3 from Loss of Rad51c leads to embryonic lethality and ...

Restoration of reduced ERK activation by IGF1 mitigates Trp53-induced ...

Generation of Trp53/Pten mice associated with luciferase expression. A ...

A schematic illustration of the for TP53/Trp53 mutation and metastasis ...

Trp53-dependent endogenous DNA-repair target genes are activated more ...

The impact of p53 on DNA damage and metabolic activation of the ...

Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to ...

Experimental and Therapeutic Medicine

Human TP53 gene, known RNA transcripts and protein isoforms. a ...

The pathogenesis of therapy-related myeloid neoplasms from TP53-mutant ...

Regulation of male germline transmission patterns by the Trp53-Cdkn1a ...

Frontiers | Prognostic Biomarker TP53 Mutations for Immune Checkpoint ...

Distinct outcomes from targeted perturbations of the multi-subunit ...

Sequencing of the Mastomys p53 gene (Trp53) and partial alignment with ...

Verteporfin Inhibits the Progression of Spontaneous Osteosarcoma Caused ...

PTEN Loss Expands the Histopathologic Diversity and Lineage Plasticity ...

Trp53/Pten undifferentiated pleomorphic sarcomas demonstrate immune ...

Th-MYCN/Trp53 KI/KI tumors exhibit | Download Scientific Diagram

Modelling aggressive prostate cancers of young men in immune-competent ...

| Differentiation of Trp53-null ES cells in two-dimensional culture ...

Human TP53 gene, known RNA transcripts and protein isoforms. a ...

APC and P53 mutations synergise to create a therapeutic vulnerability ...

Regulation of male germline transmission patterns by the Trp53-Cdkn1a ...

APR-246 can kill Eμ-Myc mouse lymphoma cells irrespective of their ...