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Lsm12 mediates the apparent association of NAADP to TPC2 and cell ...
Construction of the stable human TPC2 (hTPC2)-expressing cell line ...
Targeting TPC2 activity affects histamine-evoked P-selectin cell ...
Correlation of endogenous TPC1 and TPC2 expression with cell cycle ...
TPC2 overexpression markedly induced programmed cell death during ...
TPC2 depletion increases metastatic melanoma cell invasion. (A ...
Crosstalk between TPC2 and IP3R regulates Ca2+ signals: Trends in Cell ...
TPC1 and TPC2 do not affect TRPML1 function. A and B , whole- cell ...
Structural basis for inhibition of the lysosomal two-pore channel TPC2 ...
TPC2 promotes choroidal angiogenesis and inflammation in a mouse model ...
TPC2 targeting evolution: Leveraging therapeutic opportunities for ...
Diagrammatic depiction of TPC2 role in metabolic reprogramming in ...
Frontiers | Endolysosomal Ca2+ Signaling in Cancer: The Role of TPC2 ...
Hypoxia-induced TPC2 transcription and glycosylation aggravates ...
TPC2 controls pigmentation by regulating melanosome pH and size | PNAS
TPC2 localizes to PDGs in MEG-01 cells. (A–E) Spinning-disk confocal ...
MITF signalling pathways and proposed effects in TPC2 knockout melanoma ...
TPC2 and TRPML1 channels generate independent Ca 2þ nanodomains. Ca 2 ...
Targeting TPC2 sensitizes acute lymphoblastic leukemia cells to ...
TPC1 and TPC2 are not expressed in the plasma membrane in MEG01 and ...
Silencing TPC2 expression attenuates the rate and extent of Ca 2+ in fl ...
TPC2 is the pore-forming subunit of an NAADP-gated channel. A ...
TPC2 expression in the melanoma patient dataset and the generation of a ...
TPC2 co-immunoprecipitates with STIM1 and Orai1 in MEG01 cells. Cells ...
Role of lysosomal channel protein TPC2 in osteoclast differentiation ...
tPC2 signaling inhibited autophagy by increasing lysosomal ph in heLa ...
The endosomal calcium channels TPC1 and TPC2 are necessary for EBOV ...
Levels of TPC1 and TPC2 mRNA relative to β-actin mRNA (A). Western-blot ...
TPCs are N-glycosylated. A, schematic depictions of TPC1 and TPC2 ...
TPC2 regulates melanosomal pH to modulate pigmentation. (a) Histogram ...
Diagrammatic depiction of TPC2 role in metastatic melanoma. The ...
TPC2 localizes to melanosomes in pigment cells. (a) GFP-tagged TPC2 ...
A gain-of-function TPC2 variant R210C increases affinity to PI(3,5)P2 ...
TPC2 overexpression alkalizes the lumen of PDGs. (A) Localization of ...
Ions switch off darkness: role of TPC2 in melanosomes - Patwardhan ...
TPC2 targeted to the plasma membrane is uncoupled from ryanodine ...
Co-activation of endogenous TPC2 evokes global Ca²⁺ signals a, b Effect ...
Effect of TPC2 overexpression on autophagy. A , overlaid confocal ...
TPC2 knockdown inhibited neuronal differentiation from mouse ES cells ...
TPC2 localizes to PDGs in primary MKs. (A) Spinning-disk confocal ...
TPC2 agonists synergistically activate TPC2 a Differential effects of ...
Neurodegenerative Lysosomal Storage Disorders: TPC2 Comes to the Rescue!
Cell fate bias in tpc2⁻ cells. (a) Chimeric development. Exponentially ...
Lysosomal TPC2 channels disrupt Ca2+ entry and dopaminergic function in ...
TPC2 signaling inhibited the progression of autophagy during neural ...
Agonist-mediated switching of ion selectivity in TPC2 differentially ...
Inside-out recordings of plasma membrane-targeted TPC2 show altered ...
TPC2 agonists differentially affect lysosomal pH and proton ...
TPC2 signaling increased lysosomal pH to suppress autophagy ...
The growth and developmental phenotypes of tpc2 − cells are dependent ...
Early developmental responses are altered in tpc2 − cells. a Schematic ...
The two pore channel TPC2 is dispensable in pancreatic β-cells for ...
TPC2 did not inhibit general endosomal-lysosomal degradation in HeLa ...
| Schematic representation of the role of TPC2 in the... | Download ...
Frontiers | Endolysosomal transient receptor potential mucolipins and ...
Ca 2 , not mTOR, was involved in TPC2-induced autophagosome ...
Targeting the two-pore channel 2 in cancer progression and metastasis
Frontiers | Two-pore channel regulators - Who is in control?
A Role for Two-Pore Channel Type 2 (TPC2)-Mediated Regulation of ...
P-selectin-dependent leukocyte adhesion is governed by endolysosomal ...
Gene editing and synthetically accessible inhibitors reveal role for ...
The Two-pore channel (TPC) interactome unmasks isoform-specific roles ...
TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion ...
Altered properties of acidic vesicles in tpc2⁻ cells. a Intracellular ...
Small molecule agonist TPC2-A1-N increases intracellular Ca2 ...
EBOV enters cells through LE/Lys that contain both NPC1 and TPC2. (a ...
TPC2) Expression Increases the Metastatic Traits of Melanoma Cells by a ...
Two-pore channel-2 and inositol trisphosphate receptors coordinate Ca2 ...
Proliferation, migration, and invasion in WT and TPC2−/− MNT-1 cells ...
Developmental delay of tpc2⁻ cells. Parental Ax2 and tpc2⁻ cells were ...
Tissue and subcellular expression of mammalian TPC2.a, Hydropathy plot ...
Two Pore Channel 2 (TPC2) Inhibits Autophagosomal-Lysosomal Fusion by ...
Ca²⁺ responses in tpc2⁻cells. a Ax2- and tpc2-null cells were developed ...
Targeting Two-Pore Channels: Current Progress and Future Challenges ...
Adrenaline stimulates glucagon secretion by Tpc2-dependent Ca2 ...
Pathological tau disrupts lysosomal Ca 2+ and pH homeostasis by ...
Bringing lysosomal patch clamp recording to HTS | AXXAM
Rabbit TPC1, TPC2, and TPC3 are distantly related and exhibit ...
