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MPEP decreases SORT1 expression and increases extracellular PGRN in ...
SORT1 ligands competitively inhibit PGRN endocytosis. (A–C) Structure ...
GRN levels are regulated by SORT1 and TMEM106B expression. A, HAP1 PGRN ...
A model for PGRN lysosomal targeting. PSAP and Sortilin are two ...
| Up-regulation of plasma or CSF PGRN levels in K1-67-treated mice ...
Pgrn induces outgrowth independent of Sort1. (A) Western blot analysis ...
PGRN interactions, trafficking, and proteolysis. Several PGRN receptors ...
SORT1 triggers endocytosis of rPGRN. (A) Western blot analysis of ...
Targeting SORT1 To Unlock The Potential Of PeptideDrug Conjugates in ...
| Detailed characterization of anti-SORT1 mAb K1-67. (A) PGRN ...
PGRN activated PI3K/Akt/GSK-3β signalling pathway and the expression of ...
Progranulin (PGRN) structure and its derivative products. PGRN is ...
PGRN and its biological effects in pathogenesis of breast cancer ...
PGRN Inhibits Early B‐cell Activation and IgE Production Through the ...
SORT1 co‐expression genes in HCC (LinkedOmics). (A) Overall ...
SORT1 mRNA levels correlate with the concentration of circulating ...
Overexpression or knockdown of Sort1 in mouse liver alters plasma ...
SORT1 Mutation Resulting in Sortilin Deficiency and p75NTR Upregulation ...
SORT1 mRNA expression level in HCC. (A) SORT1 expression level in tumor ...
Schematic model of the proposed signal pathways of PGRN effect in ...
| PGRN bridges the interaction between PSAP and sortilin and ...
Co-expression of sortilin with PGRN leads to decreased extracellular ...
Knockdown of PGRN expression in vitro reduces the cholangiocyte ...
PGRN processing in Sortilin-and PSAP-deficient mice. (A,B) Western blot ...
Neurotensin receptor SORT1
PGRN processing is lysosome-dependent. a Primary Sort −/− , Grn −/− ...
SORT1 upregulation in HCC cell lines in vitro. (a) SORT1 protein levels ...
Variability in CSF PGRN levels explained by genetic variants. (A ...
Biological effects of PGRN. Increased expression of PGRN promotes ...
PGRN content in LCLs from WT controls and heterozygous and homozygous ...
SORT1 Sortilin expression is increased in GBM vs. low grade gliomas ...
PGRN levels are decreased in neurons in Sortilin-deficient mice. (A ...
Increased serum PGRN levels in sortilin-deficient mice. PGRN levels in ...
Schematic diagram summarizing the strategies applied to inhibit ...
Misregulation of human sortilin splicing leads to the generation of a ...
Frontiers | Anti-sortilin1 Antibody Up-Regulates Progranulin via ...
Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal ...
Proposed model for TDP-43 LOF effects on the PGRN-SORT1 axis in murine ...
Summary of our findings. Progranulin (PGRN) activates endothelial ...
Sortilin and PSAP comprise two independent and complementary pathways ...
(PDF) Inter-Species Differences in Regulation of the Progranulin ...
Progranulin/PGRN Antibody [Unconjugated] (AF2420): Novus Biologicals
Sortilin-Mediated Endocytosis Determines Levels of the Frontotemporal ...
靶向SORT1/Sortilin:Alector公布治疗神经退行性疾病II期临床数据 - 知乎
Anti-sortilin1 Antibody Up-Regulates Progranulin via Sortilin1 Down ...
The Role of Progranulin (PGRN) in the Pathogenesis of Glioblastoma ...
Small-molecule and antibody binders of the PGRN588–593 motif inhibit ...
The Role of Progranulin (PGRN) in the Pathogenesis of Ischemic Stroke ...
新靶点:一文读懂SORT1/Sortilin全球在研及临床进展汇总 - 知乎
Adipogen—Progranulin (human) ELISA Kit (mAb/mAb)-CSDN博客
Lysosomal functions of progranulin and implications for treatment of ...
Effect of Sortilin1 on promoting angiogenesis and systemic metastasis ...
Frontiers | Regulatory Roles of Sortilin and SorLA in Immune-Related ...
Sortilin/SORT1 General Information | Sino Biological
SORT-PGRN interaction inhibitor 1 | Sortilin-Progranulin Interaction ...
Progranulin Maintains Blood Pressure and Vascular Tone Dependent on ...
sortilin表达调控的基本机制及其运输功能。,Journal of Cellular Physiology - X-MOL
The Membrane Protein Sortilin Is a Potential Biomarker and Target for ...
Network Proteins of Human Sortilin1, Its Expression and Targetability ...
神经紧张素受体SORT1
BVFP | PGRN-SORT1结合抑制剂/SORT1拮抗剂 | TargetMol
科学网—Nature Communi——额颞叶痴呆PGRN突变导致prosaposin运输异常 - 陈之春的博文
Genome-wide Screen Identifies rs646776 near Sortilin as a Regulator of ...
Sortilin-dependent regulation of progranulin action in prostate cancer ...
Inter-Species Differences in Regulation of the Progranulin–Sortilin ...
Role of sortilin 1 (SORT1) on fatty acid–mediated cholesterol ...
Role of sortilin 1 (SORT1) on lipid metabolism in bovine liver ...
Discovery of Small‐Molecule Inhibitors Targeting Progranulin‐Sortilin ...
Sorting Out Frontotemporal Dementia?: Neuron
靶向SORT1/Sortilin:Alector公布AL001治疗神经退行性疾病INFRONT-2 II期临床数据 - 知乎
Investigating the Conformational Response of the Sortilin Receptor upon ...
#sort1 #sortilin #lsd #frontotemporal #dementia #vincoai #pgrn ...
Sortilin 1 regulates hepatocellular carcinoma progression by activating ...
SORT-1 项目配置运行-WINDOWS_sort跟踪 配置运行-CSDN博客
Sort1, Encoded by the Cardiovascular Risk Locus 1p13.3, Is a Regulator ...
| JIR | Dove Medical Press
| PGRN-and sortilin-deficient mice display PSAP trafficking defects ...