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Schematic representation of the key enzymatic function of IDH1 and IDH1 ...
Proposed model of mutant IDH1 function in chondrosarcoma cells ...
Comparison of the function of the IDH1 enzyme (wild-type) and its ...
IDH1 Function Supports the Activity of α -KG-Dependent Dioxygenases In ...
Compensation for wild-type IDH1 loss of function in GBM tumors ...
Inhibition of IDH1 R132H function in vivo results in an enhanced IFNɣ ...
IDH1 supports mitochondrial function under nutrient withdrawal in ...
HIF-1α contributes to the tumorigenic function of IDH1 mutation in ...
Effect of IDH1 substrate α-KG on the biological function of RCC cell ...
The IDH1 R132 mutant is shown as an example to illustrate how a ...
IDH1 is a cytosolic protein with enzymatic activity. A point mutation ...
Enzymatic function of wild-type and mutant IDHs and supposed mechanism ...
IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and ...
Clinical development of IDH1 inhibitors for cancer therapy - Cancer ...
Implications of Concurrent IDH1 and IDH2 Mutations on Survival in ...
The role of IDHs. IDH1 is located in the cytosol and the peroxisomes ...
IDH1 and IDH2 mutations in myeloid neoplasms – Novel paradigms and ...
IDH1 mutation promotes 2-HG production in NSCLC cells. (a) 2-HG levels ...
Full article: The Roles of IDH1 in Tumor Metabolism and Immunity
Gene of the month: IDH1 | Journal of Clinical Pathology
IDH1 and IDH2 mutations causes build up of 2-hydroxygluatrate (2-HG ...
Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2 ...
Overexpression of IDH1 constructs in U87 cells. Protein expression ...
IDH1-mediated metabolic reprogramming. In general, IDH1 mutation ...
| The overexpression of IDH1 promoted cell proliferation of ...
Schematic representation of IDH1 and IDH2 mutations determining the ...
Expression of IDH1 R132H alters metabolism in the TCA cycle in U87 ...
Energy Metabolism in IDH1 Wild-Type and IDH1-Mutated Glioblastoma Stem ...
IDH1-dependent α-KG regulates brown fat differentiation and function by ...
IDH1 and IDH2: Not Your Typical Oncogenes: Cancer Cell
Y42 phosphorylation of IDH1 by group I TKs promotes protein ...
IDH1 mutation is sufficient to establish the glioma hypermethylator ...
The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a ...
(A) Illustration of isocitrate dehydrogenase (IDH) function change with ...
Frontiers | Recent advances of IDH1 mutant inhibitor in cancer therapy
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted ...
Site of mutation in IDH1 gene is R-132 and in IDH2 gene is R-172 ...
FOXOs mediated regulation of IDH1. IDH1 is directly regulated by FOXO ...
IDH1 mutations in five head and neck cancer studies (cBioPortal). A ...
Scutellarin activates IDH1 to exert antitumor effects in hepatocellular ...
IDH1 mutation-mediated inhibition of cell proliferation depends on ...
LncRNA IDH1-AS1 links the functions of c-Myc and HIF1α via IDH1 to ...
IDH1 Mutation Promotes Tumorigenesis by Inhibiting JNK Activation and ...
Frontiers | Differential metabolic alterations in IDH1 mutant vs ...
IDH1 Gene - GeneCards | IDHC Protein | IDHC Antibody
MetaMapp- visualizing metabolomics networks: Effect of IDH1 mutations ...
IDH1-AS1 altered IDH1 enzyme activity without affecting IDH1 mRNA or ...
Gliomagenesis, prognosis and immunomodulation rendered by IDH1 status ...
IDH variant inhibitors bind wt IDH1 (teal) and IDH1 R132H (orange) with ...
Metabolic reprogramming in IDH1-mutated glioma. Acquisition of IDH ...
Frontiers | IDH1: Linking Metabolism and Epigenetics
Overview of IDH1's biological role in normal cellular functions and the ...
IDH pathway. Wild type and mutant type | Download Scientific Diagram
Krebs cycle to DNA methylation. IDH1/2 wild-type enzymes convert ...
Isocitrate dehydrogenase/IDH1 Protein Overview | Sino Biological
Targeting Cancer Metabolism
Gliomas
Metabolic adaptations in cancers expressing isocitrate dehydrogenase ...
IDH Inhibitors and Immunotherapy for Biliary Tract Cancer: A Marriage ...
(PDF) In silico gene expression analysis reveals glycolysis and acetate ...
Isocitrate dehydrogenase mutations in hereditary diseaes | PPTX
Roles of IDH1/2 and TET2 mutations in myeloid disorders | SpringerLink
Consequences of IDH1/2 Mutations in Gliomas and an Assessment of ...
IDH mutations in cancer and progress toward development of targeted ...
Wild-Type Isocitrate Dehydrogenase-Dependent Oxidative Decarboxylation ...
Figures
Clinical Implications of Isocitrate Dehydrogenase Mutations and ...
Frontiers | Biological Roles and Therapeutic Applications of IDH2 ...
Catalytic functions of the wild-type and mutated IDH1/IDH2 enzymes. In ...
The Distribution and Significance of IDH Mutations in Gliomas | IntechOpen
Mutant IDH in Gliomas: Role in Cancer and Treatment Options
Molecular Targeting of the Isocitrate Dehydrogenase Pathway and the ...
Isocitrate Dehydrogenase Mutations in Myelodysplastic Syndromes and in ...
(PDF) IDH1: Linking Metabolism and Epigenetics
(PDF) Mak TW Regulation of cancer cell metabolism
Oncogenic Activities of IDH1/2 Mutations: From Epigenetics to Cellular ...
Characterization of IDH1-mutant-induced gene expression... | Download ...
Figure 1.
Hyperthermia as a Potential Cornerstone of Effective Multimodality ...
The relation between IDH1/2 and 2-HG. (a) Wild-type IDH1/2 and (b ...
Molecular Medicine Reports
Representative image of the functions of mutant IDH1/2 in gliomas. In ...
The Three Major Metabolic Pathways In Peroxisomes
Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic ...
TF by IDH1/2 status in gliomas. a Mean increase in methylation beta ...
Isocitrate Dehydrogenase Mutations in Human Cancers: Physiopathologic ...
Surgical Neurology International
Biology丨IDH1 通过促进巨噬细胞铁死亡从而生成泡沫细胞 - 知乎
Recent findings on molecular alterations in IDH1, TP53, and CASP9 in ...
Wild-Type IDH Enzymes as Actionable Targets for Cancer Therapy
Functional implication of IDH1/2 mutations in central neuron ...
Research timeline of cancer energy metabolism reprogramming and IDH1/2 ...
Contribution of metabolic abnormalities to acute myeloid leukemia ...
Relationship between IDH mutations and other genetic alterations in ...
An example of gain-of-function mutation. Most of the gene mutations ...
Enzyme activity of IDH1/2 wildtype and IDH1/2 mutant. IDH1/2 catalyzes ...
Frontiers | Genetics and Epigenetics of Glioblastoma: Applications and ...
The genetic status of IDH1/2 and EGFR dictates the vascular landscape ...
From genomics to the clinic: biological and translational insights of ...
New Developments in the Pathogenesis and Therapeutic Targeting of the ...
Activity of high-dose vitamin C in tumors with TETs, IDH1/2 or WT1 ...
